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KMID : 0358420110540060330
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Korean Journal of Obstetrics and Gynecology
2011 Volume.54 No. 6 p.330 ~ p.333
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Angiomyofibroblastoma of the uterine cervix in a breast cancer patient: A case report
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Kim Min-Ji
Kuk Jin-i
Sung Ji-Hyun
Shim Soon-Sup
Hyun Chang-Lim
Park Chul-Min
Kim Sung-Yob
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Abstract
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Angiomyofibroblastoma (AMFB) is a rare mesenchymal tumor mostly involving the female lower genital tract. Although a large number of cases of vulva and vagina has been reported, a report on a case of the uterine cervix is uncommon. Despite unknown pathogenesis of AMFB, positive immunoreactivity for hormonal receptor of AMFB allows to make an assumption that the hormonal stimuli may have a role on the development of AMFB. Therefore, it is potential that estrogenic effect of tamoxifen gives stimuli on hormonally responsible mesenchymal cells, resulting in AMFB. We report a case of AMFB of the uterine cervix in a breast cancer patient with prolonged tamoxifen treatment with brief literature review.
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KEYWORD
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Angiomyofibroblastoma, Cervix uteri, Breast neoplasm, Tamoxifen
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